Author/Editor     Potočnik, Marko; Kocjan, Boštjan; Seme, Katja; Luzar, Boštjan; Babič, Dunja Z; Poljak, Mario
Title     Beta-papillomaviruses in anogenital hairs plucked from healthy individuals
Type     članek
Source     J Med Virol
Vol. and No.     Letnik 78, št. 12
Publication year     2006
Volume     str. 1673-8
Language     eng
Abstract     A total of 150 specimens of anogenital hairs plucked from the scrotal, pubic, and perianal region of 51 immunocompetent healthy male individuals were tested for the presence of beta-papillomaviruses (beta-HPV) using the nested M(a)/H(a) polymerase chain reaction. Beta-HPV were found in a total of 38 (25.3%) of 150 hair samples. According to the sampling sites, beta-HPV were detected in 18/51 (35.3%), 13/50 (26.0%), and 7/49 (14.3%) plucked hair samples obtained from the pubic, scrotal, and perianal region, respectively. The prevalence of beta-HPV in the plucked pubic hairs was significantly higher than in the perianal hairs (P = 0.013). In contrast, the difference in the prevalence of beta-HPV in the pubic and scrotal hairs as well as in scrotal and perianal hairs did not reach statistical significance (P = 0.302 and P = 0.227, respectively). The difference in the lifetime-cumulative sun exposure is the most likely explanation for the differences obtained on beta-HPV prevalence. Beta-HPV genotype HPV-38 was detected most frequently, followed by HPV-36, HPV-15, and HPV-14D. In addition to the beta-HPV recognized officially five partial DNA sequences suggesting putative new HPV genotypes were identified.
Descriptors     IMMUNOCOMPETENCE
ADULT
DNA, VIRAL
GENOTYPE
HAIR
MOLECULAR SEQUENCE DATA
PHYLOGENY
PREVALENCE
PUBIC SYMPHYSIS
SCROTUM
SEQUENCE ANALYSIS, DNA