Author/Editor		Vujasinović, Miroslav; Tepeš, Bojan
Title		Nealkoholna zamaščenost jeter
Translated title		Nonalcoholic fatty liver disease
Type		članek
Source		Gastroenterolog
Vol. and No.		Letnik 10, št. 22
Publication year		2006
Volume		str. 41-7
Language		slo
Abstract		Nonalcoholic fatty liver disease is a clinicopathological entity characterized by histological spectrum that ranges from steatosis to steatohepatitis, fibrosis and cirrhosis. It is highly recognized condition and is considered the hepatic manifestation of the metabolic syndrome. It is commonly characterized by elevated plasma liver enzyme levels and is more common in obese, diabetic and hyperlipemic patients. Liver biopsy is the gold standard for diagnosis. Prognosis is generally good, but occasionally cirrhosis and liver failure developed. No specific pharmacological treatment is available at the moment. Nonalcoholic fatty liver disease will probably become the most frequent liver ailment in the next decades.
Summary		Nealkoholna zamaščenost jeter je kliničnopatološki sindrom s širokim spektrom histološliih sprememb, od steatoze do steatohepatitisa, fibroze in ciroze. Gre za pogosto bolezen, ki je jetrna komponenta metaboličnega sindroma. Zanj so značilne povišane vrednosti transaminaz in je pogostejša pri bolnikih z diabetesom in hiperlipidemijo. Za diagnozo je odločilnega pomena biopsija jeter. Prognoza je načeloma dobra, vendar pri posameznih bolnikih bolezen lahko napreduje do ciroze in jetrne odpovedi. Zaenkrat ni učinkovite farmakološke terapije. Nealkoholna zamaščenost jeter bo v naslednjih desetletjih verjetno postala najpogostejša jetrna boleren.
Descriptors		FATTY LIVER LIVER CIRRHOSIS