Author/Editor		Grošelj-Grenc, M; Sedmak, M; Glavnik, V
Title		Hepatopatija, pridružena alergiji na kravje mleko - prikaz dveh primerov
Translated title		Hepatopathy associated with cow's milk allergy - two case reports
Type		članek
Source		Slov Pediatr
Vol. and No.		Letnik 13, št. 4
Publication year		2006
Volume		str. 223-9
Language		slo
Abstract		Background. Cow's milk allergy is one of the commonest food allergies in childhood. It can effect the gastrointestinal tract. skin and/or respiratory system and, in its most severe form, it can manifest as anaphylactic shock. Mild elevation of serum aminotransferases without hepatfe synthetic dysfunction is a relatively common finding in infancy. The differential diagnosis includes infections. anatomical conditions, metabolic and hereditary disorders, toxic injury and other causes. Case reports. We present two patients with cow's milk allergy in whom hepatopathy was found. In both cases the cow's milk allergy was proven by elevated concentration, of total serum IgE and milk-specific lgE. The levels of serum aminotransferases decreased or normalised after elimination of cow's milk fomules. Conclusions. Hepatopathy may be associated with cow's milk allergy. In infants showing isolated elevation of serum aminotransferases, cow's milk allergy should be considered in the differential diagnosis. Key words: hepatopathy, cow's milk allergy, cetirizine.
Summary		Izhodišča. Alergija na kravje mleko je ena najpogostejših alergij na hrano v otroštvu. Kaže se lahko s prizadetostjo prebavil, kože in/ali dihal ter v najhujši obliki kot anafilaktični šok. Blago zvišane serumske koncentracije aminotransferaz brez jetrne okvare so razmeroma pogosta najdba v obdobju dojenčka. Diferencialna diagnoza hepatopatije vključuje okužbe, anatomske vzroke, presnovne in dedne vzroke, toksične okvare ter druge vzroke. Prikaz primerov. Prikazani sta dve bolnici z alergijo na kravje mleko in ugotovljeno hepatopatijo. V obeh primerih je bila alergija na kravje mleko potrjena z zvišanimi celokupnimi IgE in specifičnimi IgE na kravje mleko. Po uvedbi stroge diete so se serumske koncentracije aminotransferaz znižale oziroma normalizirale. Zaključki. Hepatopatija je lahko pridružena alergiji na kravje mleko. Pri dojenčkih s povišanimi aminotransferazami je treba diferencialnodiagnostično misliti na alergijo na kravje mleko.
Descriptors		MILK HYPERSENSITIVITY BOTTLE FEEDING LIVER DISEASES CETIRIZINE INFANT