| Abstract | | To elucidate the pattern of postocclusive reactive hyperaemia (PRH and the contribution of metabolic and myogenic component we exposed a peripheral vascular bed to different intravascular pressures and to ischemia of varying duration. Skin blood flow was monitored using laser-Doppler (LD) flowmeter in nine healthy volunteers after the occlusion (1, 4, 8 min) of digital arteries. The area under the first part of PRH flow curve was characterized by its dependence on the duration of occlusion p < 0,05, Bonferroni t-test) but showed no dependence on the estimated blood pressure in the digital arteries. This suggests the predominant role of the metabolic component in this part of PRH response. The second descending part of PRH response was characterized by periodic oscillations (mean fundamental frequency 0,12 f 0,025 Hz). The duration of occlusion had no effect on this part of PRH, but the increase of the estimated blood pressure in the digital arteries significantly increased the frequency of oscillations (lin. regression, b = 0,08, p < 0,001). This suggests a predominant role of the myogenic component in this part of PRH. (Abstract truncated at 2000 characters)
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