Author/Editor		Kotnik, Vladimir; Pirš, Branko; Potočnik, Marko
Title		Sifilis pri novorojenčku
Translated title		Syphilis in newborn child
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 45, št. Suppl 3
Publication year		2006
Volume		str. 91-5
Language		slo
Abstract		Syphilis in newborn child may be congenital or connatal. Together with the clinical signs serological testing is obligatory for confirmation of the disease. For laboratory testing of newborn child's serum or plasma the same tests as for the adults are appropriate (VDRL or RPR, TPHA or TPPA, FTA-ABS IgG and FTA-ABS IgM, ELISA and LIA). Important is that samples from mother and child are taken almost at the same time, because only at that circumstances comparisons of the antibody titers and diagnosis will be adequate. Cord blood is inappropriate sample. Syphilitic pregnant woman should be treated with adequate antibiotics with the clear evidence that treatment was successful, in other case transmission of the disease to the child could be expected with rely. Syphilis in newborn child is very uncommon in Slovenia. The last clinically evident case was reported back in the year 1985, but we can never know when the next case will emerge!
Summary		Sifilis pri novorojenčku je lahko prirojen - kongenitalen ali pridobljen med porodom - konatalen. Poleg kliničnih znamenj je za diagnostiko sifilisa pri novorojenčku potrebno serološko testiranje. Testi, ki jih uporabljamo, so enaki kot tisti, ki jih rabimo za diagnostiko pri odraslih preiskovancih (VDRL ali RPR, TPHA ali TPPA, FTA-ABS IgG in FTA-ABS IgM, ELISA in LIA). Vzorce seruma ali plazme je treba izbrati primerno času, ki je potekel od okužbe. Popkovna kri je neprimeren vzorec. Najustrezneje primerjamo titre protiteles pri materi in otroku, če kri odvzamemo obema istočasno kmalu po porodu. Sifilitično nosečnico je treba nujno pozdraviti, drugače lahko upravičeno pričakujemo, da bo zbolel tudi plod ali novorojenček. Sifilis pri novorojenčkih je v naših krajih izjemno redek. Zadnji znan primer z izrazito klinično simptomatiko je iz leta 1985, kljub temu pa ni nemogoče, da se ne bi rodil otrok s prirojeno ali pridobljeno obliko sifilisa.
Descriptors		SYPHILIS, CONGENITAL TREPONEMA PALLIDUM INFANT, NEWBORN