Author/Editor		Kocijančič, Ksenija; Kocijančič, Igor
Title		Radiofrequency ablation of lung tumours - new perspective in treatment of lung neoplasms
Translated title		Radiofrekvenčna ablacija pljučnih tumorjev - nova oblika zdravljenja pljučnih novotvorb
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 41, št. 1
Publication year		2007
Volume		str. 33-8
Language		eng
Abstract		Background. Percutaneous radiofrequency ablation (RFA) is a minimally invasive technique used to treat solid tumours. Because of its ability to produce large volume of coagulation necrosis in controlled fashion this technique has been progressively tested as a possible treatment of lung malignancies. Recent clinical studies have shown that RFA enables successful treahnent of relatively small lung malignancies with high rate of complete response and acceptable morbidity and have suggested that the technique could represent a viable alternate or complementary method for patients with non-small cell lung cancer or lung metastases of favourable histotypes who are not candidates for surgical resection. Conclusions. Initial intenational studies as well as the clinical experience of Institute of Radiology in Clinical Center Ljubljana, although limited, indicated that RFA is mostly well tolerated by patients and also, that it can result in complete necrosis of targeted lesion. Pneumothorax is most common procedure related complication, occurring in up to 40% of cases, with approx. half of them requiring drainage.
Summary		Izhodišča. Perkutana radiofrekvenčna ablacija (RFA) je minimalno invazivna tehnika zdravljenja solidnih tumorjev. Preizkušati so jo začeli tudi kot možen postopek zdravljenja pljučnega raka in zasevkov, ker lahko z njo v kontroliranih pogojih dosežemo obsežnejša področja koagulacijske nekroze. Na ta način lahko uspešno zdravimo sorazmerno majhne zločeste spremembe v pljučih. RFA je sprejemljiva zamenjava ali dodatna metoda zdravljenja za bolnike z nedrobnoceličnim pljučnim rakom ali s pljučnimi zasevki drugih rakov, ki jih iz različnih vzrokov ne moremo operirati. Zaključki. Dosedanje mednarodne klinične raziskave pa tudi začetne izkušnje Inštituta za radiologijo v Kliničnem centru Ljubljana so pokazale, da zdravljenje z RFA bolniki sorazmerno dobro prenašajo in da lahko s to metodo zdravljenja dosežemo popolno nekrozo tkiva v tarčnem volumnu. Najpogostejši zaplet je pneumotoraks (do 40%), pri polovici bolnikov s tem zapletom pa je potrebna torakalna drenaža.
Descriptors		LUNG NEOPLASMS CATHETER ABLATION