Author/Editor		Homšak, Matjaž; Koren, Brigita; Tomazin, Maja; Brunčko, Aleksander
Title		Alergija in imunski odziv
Translated title		Allergy and the immunological response
Type		članek
Source		In: Gregorič A, editor. Metabolični sindrom pri otrocih, sodobni način življenja in imunski odziv pri otrocih, racionalna uporaba zdravil v pediatriji. Zbornik 17. srečanje pediatrov v Mariboru in 4. srečanje medicinskih sester; 2007 apr 13-14; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2007
Volume		str. 123-7
Language		slo
Abstract		In allergy the immunological response to foreign triggers is mostly modulated by Th2 lymphocytes. The Th2 response, however, only partly explains the disease pictures in allergy. The final type of allergy - phenotype is formed by environmental triggers in combination with a genetic disposition. Recent studies have confirmed the very different immunological responses within the same phenotype of allergic disease. Infants with wheezing are exposed to different viral infections, which can increase or decrease the risk of asthma in later life. Interestingly, these children rarely develop allergic rhinitis. The atopic march theory is less probable in children with atopic dermatitis. Children with atopic dermatitis more frequently develop allergic rhinitis than asthma. Allergic children have a reduced Th1 response, which leads to a higher susceptibility to respiratory infections, which last longer. The association between malignant diseases and allergies is confirmed in some types of cancer, but not in others. Study results are very contradictory. By increasing the number of observed cases and cooperation in research new truths about the immune response can be confirmed. This is perhaps an opportunity to discover new diseases.