Author/Editor		Volavšek, M; Ferluga, D; Malovrh, M; Jakša, I
Title		Bubrežne promene kod panarteritisa nodosa
Translated title		Renal changes in panarteritis nodosa
Type		članek
Source		Mak Med Pregl
Vol. and No.		Letnik 43, št. Suppl 9
Publication year		1989
Volume		str. 135-6
Language		cro
Abstract		The diagnosis of panarteritis nodosa (PN) has to be confirmed with clinical and histological features. It is belived that the kidneys are affected in up to 85 percent of cases. We studied renal biopsy and autopsy samples of 12 patients with PN to compare their patomorphologic features with other authours. All samples were processed according to standard techniques for light microscopy and immunofluorescence. 3 patients had classical PN: 1 of them showed focal sclerotic glomerulonephritis (GN), the second focal segmental necrotic extracapillary (Ex) proliferative and sclerotic GN and the third no changes. Blood vessels in all of them showed sclerotic and partially destructive lesions. In 9 cases with microscopic form of PN small blood vessels showed predominantly necrotic lesions and the following glomerular changes: focal segmental (6/9) and diffuse (1/9) Ex proliferative GN with associated necrotic lesions and sclerosis. We could not prove their immune complex origin.
Descriptors		KIDNEY PERIARTERITIS NODOSA GLOMERULOSCLEROSIS, FOCAL GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE BIOPSY AUTOPSY