Author/Editor		Grmec, Štefek; Klemen, Petra; Golub, Mirjam
Title		Diagnostično-prognostični pomen kardioloških označevalcev v predbolnišničnem okolju
Translated title		Diagnostic and prognostic value of cardiac markers in prehospital setting
Type		članek
Source		In: Gričar M, Vajd R, editors. Urgentna medicina: izbrana poglavja 2007. Zbornik 14. mednarodni simpozij o urgentni medicini; 2007 jun 20-23; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Publication year		2007
Volume		str. 201-3
Language		slo
Abstract		Point-of-care (POC) or "near-patient" testing allows diagnostic assays to be performed in locations such as the emergency department or intensive care unit where treatment decisions are made and care is delivered based on the results of these assays. Presently, there exist POC immunoassays for several cardiac markers including creatine kinase MB (CK-MB), myoglobin, troponin I, troponin T, ddimer, N-terminal-proBNP that yield qualitative and quantitative results comparable to traditional central lab assays. In the evaluation of emergency room patients with chest pain and/or failure and pulmonary embolism, POC cardiac markers may improve triage and clinical outcomes. Existing POC assays have high sensitivity and specificity for diagnosing acute myocardial infarction, heart failure and pulmonary embolism. POC troponin T and NT-proBNP assays are the most studied POC cardiac marker assays. These tests provide more sensitive identification of myocardial injury/ heart failure and valuable prognostic information.