Author/Editor		Benedičič, Mitja; Bernjak, Alan; Stefanovska, Aneta; Bošnjak, Roman
Title		Continuous wavelet transform of laser-Doppler signals from facial microcirculation reveals vasomotion asymmetry
Type		članek
Source		Microvasc Res
Vol. and No.		Letnik 74, št. 1
Publication year		2007
Volume		str. 45-50
Language		eng
Abstract		Facial laser Doppler flux (FLDF) consists of a mean value and complex oscillatory components called vasomotion. Vasomotion can be expressed as spectral amplitudes (SA) after the application of continuous wavelet transform. Vasomotion is influenced by cardiac activity (frequency interval I), respiration (interval II), intrinsic myogenic activity (interval III), neural mechanisms (interval IV) and endothelial mechanisms (intervals V and VI). Asymmetry of FLDF mean value was previously documented and hereby we present homogeneity assessment for FLDF vasomotion. Mean FLDF (p<0.001), total SA (p<0.001) and SA within frequency intervals I-VI were significantly higher in both cheeks compared to forehead. Total SA (p=0.009) and SA within frequency intervals I (p=0.041), II (p=0.005), III (p=0.009), IV (p=0.001) and V (p=0.036) were significantly higher in right than in left forehead. Human face is a heterogeneous microvascular region. Angiographic characteristics of deep horizontal sub-dermal plexus, endothelial and vascular smooth muscle cell heterogeneity, and plasticity of the microvasculature, autonomic asymmetry and facial neuropsychological asymmetry are possible causes of microvascular asymmetry. The origin and significance of microvascular imbalance need to be elucidated further.
Descriptors		LASER-DOPPLER FLOWMETRY SIGNAL PROCESSING, COMPUTER-ASSISTED ADULT FACE IMAGE INTERPRETATION, COMPUTER-ASSISTED MICROCIRCULATION MUSCLE, SMOOTH, VASCULAR REGIONAL BLOOD FLOW SKIN