Author/Editor     Pavčnik, Dušan; Uchida, Barry; Kaufman, John; Keller, Frederick S; Roesch, Josef
Title     Percutaneous venous valve implantation in management of chronic deep venous insufficiency: an overview of our experimental work and early clinical experience
Type     članek
Source     eská radiologie
Vol. and No.     Letnik 61, št. 2
Publication year     2007
Volume     str. 127-35
Language     eng
Abstract     To present an overview of our 7 years of experimental work and early clinical experience with percutaneous implantation of a bioprosthetic venous valve (BVV) and our recent experimental work with percutaneous autogenous venous valve (PAW) transplantation. Three types of BVVs consisting of a (small) leaflet of small intestinal submucosa (SIS) attached to different types of metallic square stent frames were tested in the ovine jugular veins. Altogether 66 BVVs were tested in 32 sheep. Follow-up venograms were done from 1 to 6 months. In clinical work, 15 patients with advanced venous insufficiency were treated by placement of a single BVV into the femoral vein. PAVV transplantation with a vein segment containing a native valve attached to a stent template ', was explored in 9 sheep. BV Vs were easy to deliver and remained in place and stable.
Descriptors     VENOUS INSUFFICIENCY
BLOOD VESSEL PROSTHESIS
JUGULAR VEINS
FEMORAL VEIN
POPLITEAL VEIN
PHLEBOGRAPHY
STENTS
TREATMENT OUTCOME
SHEEP