Author/Editor		Seme, K; Kotnik-Kevorkijan, B; Baklan, Z; Fujs, K; Babič, DZ; Poljak, M
Title		False-positive result of a confirmatory human immunodeficiency virus line immuno assay in an apparently healthy individual - a case report
Type		članek
Source		Coll Antropol
Vol. and No.		Letnik 30, št. Suppl 2
Publication year		2006
Volume		str. 43-6
Language		eng
Abstract		A case of a false-positive result of human immunodeficiency virus (HIV) confirmatory immunoblot-based assay is described. Repeatedly borderline reactive anti-HIV screening enzyme immunoassay result obtained in a local hospital resulted in directing the sample to the Slovenian HIV/AIDS Reference Laboratory. In the Reference Laboratory, both anti-HIV screening assays and confirmatory Western blot were negative, while a confirmatory test INNO-LIA HIV I/II Score (Innogenetics, Ghent, Belgium) was anti-HIV-1 positive due to sgp120 and gp41 reactivity. The results of serological testing of the second sample obtained three weeks later were completely identical, while in the third sample obtained 5 months later, seroreversion was observed. Due to a negative dynamics in anti-HIV serological profile and repeatedly negative results of the molecular tests for HIV-1 and HIV-2, HIV infection was excluded and the results of test INNO-LIA HIV I/II Score were finally interpreted as false positive.
Descriptors		HIV-1 ADULT FALSE POSITIVE REACTIONS HIV INFECTIONS IMMUNOASSAY