Author/Editor     Meško-Brguljan, Pika; Cimerman, Nina
Title     Human cystain C
Type     članek
Source     Turk J Biochem
Vol. and No.     Letnik 32, št. 3
Publication year     2007
Volume     str. 95-103
Language     eng
Abstract     Cystatin C, a low molecular weight inhibitor of cysteine proteascs, is involved in various biological and pathological processes. Recently, scrum cystatin C has been proposed to be a valuable alternative marker of glomerular filtration rate, particularly in situations in which creatinine fails to provide an accurate estimate of renal impairment. However, the use of cystatin C is interfered by nonrenal factors such as glucocorticoid therapy, malignancy or thyroid disorders, which influence scrum cystatin C concentrations. The clinical utility of cystatin C as a renal marker is under evaluation. The standardisation of methods for cystatin C is necessary.
Descriptors     CYSTATINS
GLOMERULAR FILTRATION RATE