Author/Editor		Poljšak-Prijatelj, Mateja; Steyer, Andrej; Zimšek-Mijovski, Janet; Kovač, Katarina
Title		Virusni povzročitelji črevesnih okužb
Translated title		Viral causes of gastroenteritis
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 46, št. Suppl 2
Publication year		2007
Volume		str. 61-8
Language		slo
Abstract		Acute gastroenteritis is one of the most common illnesses affecting infants, childr en and adults worldwide. The most important viral causative agents are rotaviruses, human caliciviruses (noro- and sapoviruses), enteric adenoviruses and astroviruses. In addition to these, coronaviruses, toroviruses, picobirnaviruses, non-group F adenoviruses and picornaviruses have been found in the stools of humans with gastroenteritis, but also in healthy individuals. Frequently the etiologic agent can notbe found in the specimens tested. The diagnostic gap can be reduced through the use of molecular methods. At the Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, 2.558 stool specimens from hospitalized patient were tested in the period from June 2006 to June 2007. In 1.105 (43,2 °/>) samples, viral antigens were detected using the enzyme immuno assay. Among these, caliciviruses were detected in 546 (49,4 %), rotaviruses in 336 (30,4 %), astroviruses in 45 (4 %) and adenoviruses 40/41 in 40 (3,6 %) samples. Since 1999 molecular methods have been used to determine rotavirus and calicivirus genotypes. Rotavirus genotypes G1 to G4, G8, and G9 were detected and in addition G12 was detected for the first time in Slovenia. As expected the most prevalent P genotype was P[8], a rare one was P[4], and only one strain was found to have P[6] genotype specificity. The most frequent calicivirus, i. e. norovirus genotypes, were G7II/4b and GII/4b. In the year 2006, genotype G7II - GII/7 have appeared for the first time. From outbreak specimens, genotype GI/6 were also detected.
Descriptors		GASTROENTERITIS VIRUS DISEASES ROTAVIRUS ADENOVIRIDAE CALICIVIRIDAE ASTROVIRUS TOROVIRUS