Author/Editor		Novak, Dušan; Orešić, Nadja; Reberšek-Gorišek, Jelka
Title		Helicobacter pylori epidemiološke značilnosti in diagnostične metode
Translated title		Helicobacter pylori, its epidemiologic characteristics and diagnostic methods
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 46, št. Suppl 2
Publication year		2007
Volume		str. 183-90
Language		slo
Abstract		Helicobacter pylori (H. pylori) is Gram-negative spiral bacteria which can be found worldwide. It secretes numerous enzymes and the most important one for the pathogenesis of infection is the urease enzyme. The incidence of infections among people living in underdeveloped and developed countries is high. The risk factors for infection are primarily related to poor social and economic conditions. The presence of H. pylori is detected using invasive and non-invasive methods. Invasive methods include the urease test, culture, antibiotic susceptibility test, and histological and molecular methods. The main non-invasive methods are serological tests, urea breath test, and antigen detection in stool. The sensitivity and specificity of the above-mentioned methods are high. Serological and histologYCal tests, urease test, urea breath test, and antigen detection in stool are most commonly used in clinical practice. Culture, antimicrobial susceptibility testing and molecular methods are used for epidemiologic, diagnostic, therapeutic and other research.
Descriptors		HELICOBACTER INFECTIONS HELICOBACTER PYLORI MICROBIAL SENSITIVITY TESTS ANTIGENS, BACTERIAL