Author/Editor		Štabuc, B
Title		Imunopotenciacija s citotoksičnimi zdravili in interferonom alfa pri bolnikih z melanomom
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1993
Volume		str. 142
Language		slo
Abstract		The animal experiments on synergic mice C 57 and B1/6 strains were aimed to confirm the hypothesis that human leukocyte interferon alpha in the dose of 5x10 4 IE increased the antitumoral effect of cisplatinum (0.001 mg/g body weight). Throughout the duration of the experiment, mean tumor volumes measured every other day after intraperitoneal application of the substance were significantly lower (95 From days 3-6 inteferon-alpha-2b was given in the dose of 3 MIE/m2 body weight. The cycle was repeated in 28 day intervals. Objective response to treatment (UICC criteria) was achieved 39
Descriptors		MELANOMA INTERFERON-ALPHA CISPLATIN ANIMALS, LABORATORY MICE, INBRED C57BL NEOPLASM METASTASIS LOMUSTINE VINBLASTINE BLEOMYCINS SURVIVAL ANALYSIS LEUKOCYTE COUNT LYMPHOCYTES ANTIGENS, CD CYTOTOXICITY, IMMUNOLOGIC