Author/Editor		Rudolf, Saša; Naji, Jamal; Matela, Jože
Title		Pokontrastna nefropatija
Translated title		Contrast induced nephropathy (CIN)
Type		članek
Source		Med Mes
Vol. and No.		Letnik 3, št. 6
Publication year		2007
Volume		str. 199-207
Language		slo
Abstract		Contrast - induced nephropathy (CIN) is a common and potentially serious complication that can follow the administration of iodinated contrast media to patients at risk of acute renal injury. It is an important cause of hospital - acquired renal failure, responsible for approximately 11 % of cases. The European Society of Urogenital Radiology (ESUR) defines CIN as impairment in renal function (an increase in serum creatinine by >25 % or 44.2 [micro]mol/l) within 3 days after intravascular administration of contrast medium, without alternative etiology. The acute renal failure observed after the administration of contrast media is usually transient, but it can be severe enough to require dialysis and in some cases can lead to permanent renal damage. In year 2004 CIN Consensus Working Panel established, comprised 2 radiologists, 2 cardiologists, and 2 nephrologists practicing in Europe and the United States. The group systematically reviewed the published evidence on CIN and used this, together with expert opinion drawn from clinical practice, to compile a series of consensus statements and management algorithm.
Summary		Pokontrastna nefropatija - CIN je pogost in potencialno resen zaplet, ki se pojavi po uporabi jodovega kontrastnega sredstva, pri bolnikih s tveganjem za akutno okvaro ledvic. Predstavlja pomemben vzrok bolnišnično pridobljenih akutnih odpovedi ledvic, približno 11 % primerov. Evropsko združenje za urogenitalno radiologijo (ESUR) definira CIN kot poslabšanje ledvične funkcije (porast serumskega kreatinina za > 25 % oz. 44.2 [mikro]mol/l) znotraj 3 dni po intravaskularni uporabi kontrastnega sredstva, brez druge znane etiologije. Akutna ledvična odpoved je običajno prehodna, občasno je potrebna dializa, v posameznih primerih lahko pride do trajne okvare ledvic. Leta 2004 je bila ustanovljena delovna skupina 2 radiologov, 2 kardiologov in 2 nefrologov iz Evrope in ZDA. Skupina je imela nalogo, sistematično pregledati vse do tedaj objavljene dokaze o CIN ter nato, na osnovi zbranih dokazov in mnenj strokovnjakov iz klinične prakse, izdelati priporočila in algoritem ukrepov uporabe kontrastnih sredstev pri rizičnih bolnikih.
Descriptors		KIDNEY FAILURE, ACUTE CONTRAST MEDIA KIDNEY GUIDELINES