Author/Editor		Janež, Jurij; Stražar, Peter; Vengust, Rok
Title		Vpliv vertebroplastike na degeneracijo sosednjih medvretenčnih ploščic
Translated title		Effect of vertebroplasty on adjacent intervertebral disc degeneration
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 77, št. 2
Publication year		2008
Volume		str. 125-8
Language		slo
Abstract		Bone cement, which we use in vertebroplasty, causes damage to cartilage vertehral end plate and by that diminishes the diffusion of nutrients into adjacent intervertehral disc The trim of our study was to evaluate if verlehroplasty promotes degeneration of adjacent interverlebral discs. We studied 12 vertebroplasty patients (11 women, 1 man) with average age of 71 years (56-93 years). Levels of utervertebral discs degeneration before and after operation were defined on basis of MRI and Pearce's classification of intervertebral disc degeneration. Out of 36 intervertebral discs adjacent to cemented vertebral bodies, 15 of them showed increased degenerative changes after the average time o% 19 months, 21 intervertebral discs were unchanged In control group of 66 inlervertebral discs which were not in proxi mily to cemented vertebral bodies, only 12 showed increased degenerative changes, 52 irttervertebral discs were unchanged and in 2 intervertebral discs, degenerative changes were diminished. The level of statistical significance between observed and control group was 0.007 (independent-samples t test 95% level of confidance). Results of our study are showing that vertebroplasly promotes degeneration of adjacent intervertebral discs. On basis of these resuhs we recommered the applicaliora of osteoconductive bone cement containing calcium sulfate in younger patients.
Descriptors		INTERVERTEBRAL DISK SPINAL FRACTURES OSTEOPOROSIS MAGNETIC RESONANCE IMAGING