| Author/Editor | Haložan, Katja; Pahor, Dušica | |
| Title | Diabetična retinopatija | |
| Type | članek | |
| Source | Med Mes | |
| Vol. and No. | Letnik 3, št. 12 | |
| Publication year | 2007 | |
| Volume | str. 374-85 | |
| Language | slo | |
| Abstract | Diabetic retinopathy is one of the leading causes of blindless in developed countries. Althought some risk factors for diabetic retinopathy have been determined, the exact pathogenesis is yet unknown. Diabetic retinopathy is classified into nonproliferative and proliferative form. Laser photocoagulation remains the standard treatment of diabetic retinopathy and diabetic maculopathy. Vitrectomy is indicated for more advanced cases of diabetic retinopathy, such as vitreous hemorrhage, tractional retinal detachment, combined tractional rhegmatogenous retinal detachment and tractive macular edema. Newer therapeutic options with pharmacologic agents are directed at the causative mechanisms of diabetic retinopathy. Diabetic retinopathy is increasingly treated with intravitreal triamcinolone acetate and vascular endothelial growth factor inhibitors applications. The purpose of this article is to describe current aspects of pathogenesis, classification and therapeutic options of diabetic retinopathy and diabetic maculopathy. | |
| Summary | Diabetična retinopatija je eden izmed glavnih vzrokov slepote v razvitih državah. Kljub znanim nekaterim drugim dejavnikom tveganja, natančna patogeneza bolezni še ni pojasnjena. Diabetično retinopatijo delimo na neproliferativno in proliferativno obliko. Standardno zdravljenje diabetične retinopatije in diabetične makulopatije je laserska fotokoagulacija. Vitrektomija je indicirana pri napredovalih oblikah diabetične retinopatije, kot so krvavitev v steklovino, trakcijski odstop mrežnice, kombinirani trakcijsko regmatogeni odstop mrežnice in trakcijski edem makule. Novi pristopi zdravljenja s farmakološkimi učinkovinami so usmerjeni v vzročne mehanizme nastanka diabetične retinopatije. V zdravljenju diabetične makulopatije se vedno pogosteje uporablja intravitrealno dajanje triamcinolon acetata in inhibitorjev žilnega endotelnega rastnega dejavnika. Namen članka je pregled trenutnih vidikov patogeneze, klasifikacije ter možnosti zdravljenja diabetične retinopatije in diabetične makulopatije. | |
| Descriptors | DIABETIC RETINOPATHY MACULAR DEGENERATION LASER COAGULATION DRUG THERAPY DIABETES MELLITUS |