| Author/Editor | Hojs, Radovan; Bevc, Sebastjan; Ekart, Robert; Gorenjak, Maksimiljan; Puklavec, Ludvik; Pečovnik-Balon, Breda | |
| Title | Serum cystatin C as an endogenous marker of renal function in patients with chronic kidney disease | |
| Type | članek | |
| Source | Ren Fail | |
| Vol. and No. | Letnik 30, št. 2 | |
| Publication year | 2008 | |
| Volume | str. 181-6 | |
| Language | eng | |
| Abstract | The estimation of the glomerular filtration rate (GFR) is an essential part of the evaluation of patients with chronic kidney disease (CKD). Recently, serum cystatin C has been proposed as a new endogenous marker of GFR. Authors compared serum creatinine, creatinine clearance calculated from Cockcroft and Gault formula and serum cystatin C against (51)CrEDTA clearance in 252 patients with CKD and GFR <90 mL/min/1.73 m(2). Analysis of correlations and diagnostic accuracy (receiver operating characteristic curves) of different GFR markers indicate that serum cystatin C is a more reliable marker of GFR in patients with CKD than serum creatinine. | |
| Descriptors | KIDNEY DISEASES KIDNEY FAILURE, CHRONIC CYSTATINS CREATININE GLOMERULAR FILTRATION RATE |