Author/Editor		Dolenc, Jure; Koželj, Mirta; Zver, Samo
Title		Obravnava hematoloških bolnikov, zdravljenih s kardiotoksičnimi zdravili
Translated title		Management of haematological pateints treated with cardiotoxic drugs
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 77, št. Suppl 1
Publication year		2008
Volume		str. I-19-24
Language		slo
Abstract		Background Recent advances in the treatment of malign haematological deseases with chemotherapy have led to significant improvement in prognosis and quality of life of the pacients. The same drugs can lead to development of serious cardiac side effects, especially the syndrome of heart failure. Anthracycline drugs are best known for their cardiotoxicity, the role of other drugs is less well understood. Conclusions Predisposing factors to cardiotoxicity should be taken into consideration when dealing with such pacients. Careful history, clinical examination, electrocardiography, echocardiography and NT-proBNP measurement should be performed prior and at the end of the treatment with cardiotoxic drugs. Pacients with slightest clinical, laboratory or echocardiographic parameters of developing heart failure should immediately be reffered to a cardiologist to start with appropriate treatment.