Author/Editor		Velenšek-Prestor, Veronika; Jazbec, Janez; Anžič, Jožica; Benedik-Dolničar, Majda; Kitanovski, Lidija; Rajić, Vladan
Title		Obravnava otrok in mladostnikov z imunsko trombocitopenično purpuro v letih od 2001 do 2006
Translated title		Management of children and adolescents with immune thrombocytopenic purpura between the years 2001-2006
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 77, št. Suppl 1
Publication year		2008
Volume		str. I-99-103
Language		slo
Abstract		Background We have analysed the duration time of immune thrombocytopenic purpura (ITP) in children and the influence of various risk factors such as: age at diagnosis, sex, onset of symptoms and platelet count at diagnosis on duration of ITP. Data of diagnostic workup and type of treatment in child with ITP were analysed. Patients and methods Data of 64 children with ITP, 29 boys and 35 girls who have been managed at Department of Hematology and Oncology at University Children Hospital in Ljubljana between the years 2001 to 2006 were analysed. Age at diagnosis was seven weeks to 16.2 years. Results The diagnosis of ITP was made by history, physical examination and peripheral blood count. Thrombocytopenia was severe in 42 children, moderate in 8 children and mild in 14 children. The remission was not achieved in about one half of the children. Twenty eight children were treated, whereas in 34 children »watch and wait« policy with supportive advice was used. Children older than 12 years and those who had mild thrombocytopenia at diagnosis were at higher risk for developement of chronic ITP. Conclusions In our study group overall clinical course was benign with good outcome regardless of treatment type. There were no life threatening events. Management of children with ITP requires usually nonaggressive diagnostic approach and minimal treatment with medication.
Descriptors		PURPURA, THROMBOCYTOPENIC, IDIOPATHIC CHILD ADOLESCENCE