Author/Editor     Sever, Matjaž
Title     Napor in sinkopa pri aortni stenozi odraslega človeka: simulacija z analognim elektronskim vezjem
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     2008
Volume     str. 56
Language     slo
Abstract     Background. A simulation of a physiological process is its descriptive model and usually includes parameters that allow to determine conditions of a simulation. Simulation can be used for testing hypotheses, assesment, analysis, comparison and prediciton of practically any condition in physiology. Furthermore, by close examination it is possible to analyse events and their consequences. According to various methods used, simulations can be divided in groups e.g. biological, computer, mathematical, physiological, electrical, mechanical, etc. simulation. Aim. There are many types of simulation that can be used according Co a selected problem. Duc to its high reproducibility with real physiological systems the most common type of simulation is a biological simulation. However, for a proper conduction it requires a specialised laboratory and a well chosen experimental model, usually at high cost. For these reasons computer and mathematical simulations are ever more popular alternatives. Based on a carefully designed model according to a real life data they provide us with results in a fraction of a time and cost compared to biological simu)ations. Therefore, our objective was to perform a simulation of an adult human cardiovascular system with aortic stenosis based on equivalent electronic circuits using a computer program. Hypoteses. Our research aimed at developing an equivalent electronic circuit to simulate cardiovascular system with aortic stenosis in an adult. By successful development we would be able to simulate pathophysiological conditions during exercise and exertional syncope. After analysing the results we could hypothesize about underlying mechanisms in exercise and reasons leading to exertional syncope. (Abstract truncated at 2000 characters)