Author/Editor		Mulaosmanović, V
Title		Common variable immunodeficiency and pure erythroid hypoplasia due to chronic parvovirus B-19 infection - case report
Translated title		Splošna variabilna imunska opmanjkljivost in izolirana eritroidna hipoplazija zaradi kronične okužbe s parvovirusom B-19 - prikaz primera
Type		članek
Source		Slov Pediatr
Vol. and No.		Letnik 15, št. 1
Publication year		2008
Volume		str. 67-71
Language		eng
Abstract		A 3-year-old boy developed extreme anaemia 10 days after treatment for a sore throat. He had no other symptoms. Full blood count revealed Er 0.99 1012/L, Hg 19.1 g/L, Hct 5.5 %, MCV 55.5 fL, WBC 4.18 109/L, Plt 778 109/L, no reticulocytes. Serum immunoglobulin levels were normal for age, and the bone marrow was normocellular. The treatment protocol for aregenerative anaemia was followed for 5 months, but without success. During this time serum immunoglobulin levels decreased and incapsulated bacteria were isolated on several occasions. Additional laboratory examinations, performed at St. Anna Kinderspital, Vienna, Austria, revealed pure erythroid hypoplasia due to chronic parvovirus infection, common variable immunodeficiency and hypogammaglobulinaemia. In the following 5 months the child was treated with high doses of intravenous immunoglobulins. To date, his response to the therapy has been very good.
Descriptors		COMMON VARIABLE IMMUNODEFICIENCY RETICULOCYTES PARVOVIRIDAE INFECTIONS PARVOVIRUS B19, HUMAN ANEMIA CHILD, PRESCHOOL AGAMMAGLOBULINEMIA