| Author/Editor | Marc, G; Pečar, S | |
| Title | Bioizosterija in načrtovanje peptidomimetikov | |
| Translated title | Bioisosterism and design of peptidomimetics | |
| Type | članek | |
| Source | Farm Vestn | |
| Vol. and No. | Letnik 44, št. 1 | |
| Publication year | 1993 | |
| Volume | str. 3-22 | |
| Language | slo | |
| Abstract | The role of bioisosterism in rational design of peptidomimetic drugs is presented. In the first part of the article, bioisosterical replacements of different elements of peptide backbone (peptide bond, Calpha-atom, side shains) are shown. In the second part, the design of complex bioisosteres and peptide secondary structure mimetics is described. | |
| Descriptors | PEPTIDES STEREOISOMERS DRUG DESIGN PROTEIN CONFORMATION |