Author/Editor		Malešič, I
Title		Suha kemija v laboratorijski diagnostiki
Translated title		Dry chemistry in laboratory diagnostics
Type		članek
Source		Farm Vestn
Vol. and No.		Letnik 44, št. 1
Publication year		1993
Volume		str. 37-43
Language		slo
Abstract		The introduction of dry chemistry, a technique based on reflection, is a relatively recent event in the development of clinical chemistry. The dry chemistry technique originates from the qualitative and semiquantitative urinalysis with reagent strips. The first reflection-based appliance used for quantitative blood glucose determination was glucometer. Dry chemistry is of particular importance for the selfmedication of diabetic patients. A completely new method of performing examinatoins based on dry chemistry are tests using multilayer test plates. In this method a film layer is used instead of a reagent strip and the obtained results read from the reflectometer. The report presents our own experience with the analysis of 14 clinical and biochemical parameters on the Ektachem DT system. The metabolite examination procedures used in our study were well comparable with the routine practice in our institution which complies with the accepted standards. In enzymatic tests no correlation was found among the obtained amylase-and lipase-activity values. When in patients, treated with chronic intermittent hemodyalisis, measurements of potassium serum levels were performed using the dry chemistry method, the obtained values were markedly lower compared to a different method. The reason for this reduction remained unexplained. In clinical practice medicaments have a major intluence on the results obtained by dry chemistry. The article presents some suggestions how to prevent the interference of some drugs with the procedure. The results of our study have shown that dry chemistry as an analytical technique might be acceptable to the clinical chemistry provided that examinations are performed by well trained laboratory staff.
Descriptors		CHEMISTRY, CLINICAL REAGENT KITS, DIAGNOSTIC REAGENT STRIPS DIAGNOSIS, LABORATORY