Author/Editor     Pohar-Perme, M; Andersen, PK
Title     Checking hazard regression models using pseudo-observations
Type     članek
Source     Stat Med
Vol. and No.     Letnik 27, št. 25
Publication year     2008
Volume     str. 5309-28
Language     eng
Abstract     Graphical methods for model diagnostics are an essential part of the model fitting procedure. However, in survival analysis, the plotting is always hampered by the presence of censoring. Although model specific solutions do exist and are commonly used, we present a more general approach that covers all the models using the same framework. The pseudo-observations enable us to calculate residuals for each individual at each time point regardless of censoring and provide methods for simultaneously checking all the assumptions of both the Cox and the additive model. We introduce methods for single as well as multiple covariate cases and complement them with corresponding goodness-of-fit tests. The methods are illustrated on simulated as well as real data examples. Copyright (c) 2008 John Wiley & Sons, Ltd.
Descriptors     PROPORTIONAL HAZARDS MODELS
SURVIVAL ANALYSIS
REGRESSION ANALYSIS
LIVER CIRRHOSIS, BILIARY
CYCLOSPORINE
BILIRUBIN