Author/Editor		Žgur, T; Vodušek, DB; Kržan, M; Vrtovec, M; Denišlič, M; Šibanc, B
Title		Autonomic system dysfunction in moderate diabetic polyneuropathy assessed by sympathetic skin response and Valsalva index
Type		članek
Source		Electromyogr Clin Neurophysiol
Vol. and No.		Letnik 33, št. 7
Publication year		1993
Volume		str. 433-9
Language		eng
Abstract		30 patients with moderate diabetic polyneuropathy (Stage 2 according to Dyck) were evaluated for autonomic symptoms, sympathetic skin response (SSR) and Valsalva index. Their SSR were compared to a control group of 30 healthy normal subjects. Neuropathy was confirmed by history, clinical examination and nerve conduction measurements. Although our patients had only moderate polyneuropathy autonomic dysfunction was frequent. Two thirds reported autonomic symptoms. Impotence was present in 60 percent of males. SSR amplitudes were significantly lower in diabetics (changed in 53 percent, absent in 20 percent) than in the controls. SSR abnormality correlated to some clinical and electroneurographic signs of neuropathy, suggesting similar affection of sympathetic and somatic fibres. Valsalva index was abnormal in 37 percent of patients showing no correlation to clinical, electroneurographic or SSR changes.
Descriptors		AUTONOMIC NERVOUS SYSTEM DISEASES DIABETIC NEUROPATHIES ELECTROCARDIOGRAPHY GALVANIC SKIN RESPONSE ADULT AGED AUTONOMIC NERVOUS SYSTEM DISEASES DIABETIC NEUROPATHIES HEART CONDUCTION SYSTEM IMPOTENCE MIDDLE AGE MUSCULAR ATROPHY NEURAL CONDUCTION NEUROLOGIC EXAMINATION REACTION TIME REFLEX, STRETCH SENSATION DISORDERS SKIN SYMPATHETIC NERVOUS SYSTEM