Author/Editor		Štruc-Cvitan, T; Petelin, M
Title		Obravnava bolnikov z deskvamacijskim gingivitisom
Translated title		Treatment of patients with desquamative gingivitis
Type		članek
Source		Zobozdrav Vestn
Vol. and No.		Letnik 63, št. 2-3
Publication year		2008
Volume		str. 90-6
Language		slo
Abstract		Desquamative gingivitis (DG) is a chronic gingival inflammation that is manifested clinically by erythema, epithelial desquamation; erosion, ulceration, and occasionally the presence of vesiculobullous lesions. DG is not caused by bacterial plaque. It is most commonly a manifestation of immunologically mediated disorders, such as oral lichen planus, pemphigoid or pemphigus vulgaris. DG is a relatively rare condition that affects adults after the age of 50 and is more prevalent in females. It can be the only sign of immune disease. The course of the disease is often chronic with possible exacerbations. The gingiva is sensitive to physical and chemical stimuli. Painful symptoms are present especially during exacerbations. The diagnosis of the underlying disorder is established by routine histopathological examination of the diseased tissue, often followed by direct immunofluorescence staining of frozen specimens. Indirect immunofluorescence analysis of serum usually completes the diagnostic process. The treatement of DG is mostly symptomatic with local application of corticosteroids in combination with local anaesthetics. Systemic immunosuppressive therapy is necessary in cases of extensive oral and extraoral involvement. Patients with DG often require multidisciplinary care.
Descriptors		GINGIVITIS LICHEN PLANUS, ORAL PEMPHIGOID, BULLOUS PEMPHIGUS