Author/Editor		Modic, M; Mlakar, U
Title		Naše izkušnje pri zdravljenju akutne limfoblastne levkemije odraslih
Translated title		The treatment of acute lymphoblastic leukemia in adults
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 62, št. 9
Publication year		1993
Volume		str. 377-80
Language		slo
Abstract		Background. The prognosis of acute lymphoblastic leukemia (ALL) in adults is far worse than that in children in terms of induction complete remission (61-85 per cent ) and leukemia free survival from 3 to 5 years (35 per cent ). Two different combination chemotherapy were studied in our institute. Methods. From June 1982 to September 1991 39 adult patients with ALL were treated with two different combination chemotherapy: 26 patients with regiment DOP (daunorubicin, vincristine, prednisone) and 13 patients with regiment DOCMP (daunorubicin, vincristine, cyclophosphamide, methotrexate, prednisone). Results and conclusion. In the DOP group 77 per cent of patients achived complete remission, in the DOCMP group the remission rate was 92 per cent . The percentage of remission, remission duration and survival were not signficantly different between two groups. Regiment DOCMP is quite agressive and complicate. The duration of hospitalisation in this group was longer then in DOP. In the DOP group serious side effects of high dose prednisone were recorded.
Descriptors		LEUKEMIA, LYMPHOCYTIC, ACUTE REMISSION INDUCTION