Author/Editor		Jagodič, Klemen; Bizjak, Igor; Erklavec, Marko; Poteko, Sandi; Korošec-Jagodič, Helena
Title		Zdravljenje s tamsulozinom pri kamnih v spodnji tretjini sečevoda
Translated title		Treatment with tamsulosin in patients with distal ureteral calculi
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 77, št. Suppl 4
Publication year		2008
Volume		str. IV-33-6
Language		slo
Abstract		Background Symptomatic ureteral calculi are one of the most important issues in urologist emergency clinical settings. Spontaneous passage of distal ureteral calculi is usually achieved with good hydration and spasmoanalgetic drugs. á-blocker therapy may facilitate and accelerate the spontaneous passage of ureteral stones.Patients and In retrospective study we analyzed patients with renal colic admitted to our department in methods 2006. All of them had clinical examination, urine and blood analysis, plain radiography (number, size and location of radiopaque calculi) and intravenous pyelography (kidney function and morphology). All patients with distal ureteral calcus were treated with spasmoanalgetics and with or without á-adrenergic antagonist tamsulosin. We analyzed eventual spontaneous passage of the calculi, additional procedures (splints, ureterorenoscopy, open procedures, extracorporeal shock wave lithotripsy (ESWL)). We used Student’s t-test for statistical analysis. Results 48 from 72 patients had urinary calculus 35 (73 %) of them had calculus in the distal part of ureter. 17 (49 %) of 35 patients with distal ureteral calculus were treated with tamsulosin and in all (100 %) spontaneous stone passage was observed. 18 (51 %) patients were not treated with tamsulosin and spontaneous passage was observed in 18 (65 %) patients (p = 0.000). Conclusions Tamsulosin therapy promotes expulsion of ureteral stones.
Descriptors		URETERAL CALCULI RECEPTORS, ADRENERGIC, ALPHA TREATMENT OUTCOME