Author/Editor		Beck, Halfdan; Dobritzsch, Doreen; Piškur, Jure
Title		Saccharomyces kluyveri as a model organism to study pyrimidine degradation
Type		članek
Source		FEMS Yeast Res
Vol. and No.		Letnik 8, št. 8
Publication year		2008
Volume		str. 1209-13
Language		eng
Abstract		The yeast Saccharomyces kluyveri (Lachancea kluyveri), a far relative of Saccharomyces cerevisiae, is not a widely studied organism in the laboratory. However, significant contributions to the understanding of nucleic acid precursors degradation in eukaryotes have been made using this model organism. Here we review eukaryotic pyrimidine degradation with emphasis on the contributions made with S. kluyveri and how this increases our understanding of human disease. Additionally, we discuss the possibilities and limitations of this nonconventional yeast as a laboratory organism.
Descriptors		AMIDOHYDROLASES ANIMALS EUKARYOTIC CELLS FUNGAL PROTEINS NUCLEIC ACID PRECURSORS PYRIMIDINES SACCHAROMYCES