Author/Editor		Barbič-Žagar, Breda; Ristovski, Aleksandar; Dular-Meglič, Tina
Title		Ocena učinkovitosti, varnosti in sprejemljkivosti orodisperzibilnega risperidona pri bolnikih s shizofrenijo ali bipolarno manijo in pri vedenjskih motnjah dementnih bolnikov
Translated title		Evaluation of efficacy, safety and acceptability of orodispersible risperidone in patients with schizophrenia, bipolar mania and behavioural disturbances in dementia patients
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 47, št. 3
Publication year		2008
Volume		str. 309-12
Language		slo
Abstract		Second generation antipsvchotics are currently the drugs of choice for the treatment of schizophrenia and bipolar mania, as well as for behavioural symptoms in patients with dementia. All these diseases represent an important healthcare problem in Europe, so that early treatment is recommended. Due to improved patient compliance, new pharmaceutical forms of already proven therapy are developed. Orally disintegrated tablets disintegrate rapidly in the mouth without water. Therefore, a study was conducted with risperidone (Torendo Q-Tab, Krka, d. d., Novo Mesto) in 487 patients with schizophrenia, bipolar mania and behavioural disturbances in dementia patients. Risperidone in recommended doses significantly improved symptoms in 77% of patients. Its tolerability was very good, as adverse reactions related to the medicine occurred in 11.9% of the patients. 90% of the patients were satisfied with treatment with Torendo Q-Tab, and this proved very good acceptability of our risperidone in the orodispersible formulation. The most frequent reason why patients choose Torendo Q-Tab were: easy swallowing of the medicine, easy administration/intake of the medicine, ability to take it at anyplace and anytime, greater comfort that taking the medicine is less conspicuous, improved ability to perform everyday activities.
Descriptors		SCHIZOPHRENIA BIPOLAR DISORDER RISPERIDONE DEMENTIA PERSONALITY DISORDERS TREATMENT OUTCOME