Author/Editor		Ožura, Ana; Horvat-Ledinek, Alenka; Starovasnik, Barbara; Sever, Alenka; Vodušek, David B
Title		Aleksija brez agrafije pri tumorski obliki multiple skleroze: prikaz primera
Translated title		Alexia without agraphia in tumefactive multiple sclerosis: a case report
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 78, št. 1
Publication year		2009
Volume		str. 9-12
Language		slo
Abstract		Background Alexia without agraphia is a rare deficit in which the flow of visual input from the right hemisphere is prevented from entering the language network of the left hemisphere. The cause for the syndrome is most commonly an infarction in the posterior cerebral artery region. Results A 47-year-old female patient presented with an acute onset of a failure to understand written text and a headache. Clinical examination revealed right homonymous hemianopsia and severe cognitive deficits. MRI with contrast revealed a 4 × 7 cm large periventricular parieto-temporal lesion in the deep white matter of the left hemisphere, which was pathohistologically diagnosed as MS. Conclusions Alexia without agraphia is reported for the first time due to the tumefactive variant of MS. Described complex cognitive deficit was the initial sign of multiple sclerosis.
Summary		Izhodišča Aleksija brez agrafije je redka motnja, ki se pojavlja zaradi prekinitve dotoka vizualnih informacij iz desne hemisfere velikih možganov v področja jezikovnega procesiranja leve hemisfere. Najpogosteje se pojavlja kot posledica infarkta v področju posteriorne cerebralne arterije. Rezultati V članku je predstavljen primer 47-letne bolnice, ki je bila sprejeta zaradi akutno nastalih težav pri branju in glavobola. Klinično smo poleg aleksije ugotovili še desnostransko homonimno hemianopsijo in izrazite kognitivne motnje. Opravila je magnetno resonančno slikanje glave, ki je pokazalo 4 x 7 cm veliko parietotemporalno spremembo v globoki belini leve hemisfere. Patohistološko je bila diagnosticirana kot multipla skleroza. Zaključki Predstavljamo prvi primer aleksije brez agrafije pri tumorski obliki multiple skleroze. Kompleksen kognitivni primankljaj in desna homonimna hemianopsija sta v našem primeru predstavljala znake prvega zagona multiple skleroze.
Descriptors		MULTIPLE SCLEROSIS DYSLEXIA MAGNETIC RESONANCE IMAGING BRAIN NEUROPSYCHOLOGICAL TESTS MIDDLE AGE