Author/Editor | Piškur, Jure | |
Title | A 5 kb intergenic region containing ori1 in the mitochondrial DNA of Saccharomyces cerevisiae is dispensable for expression of the respiratory phenotype | |
Type | članek | |
Source | FEBS Lett | |
Vol. and No. | Letnik 229, št. 1 | |
Publication year | 1988 | |
Volume | str. 145-9 | |
Language | eng | |
Abstract | A mutant mitochondrial DNA of Saccharomyces cerevisiae strain R 0.54 has been shown to have a 5 kb deletion which removes the ori1 sequence and its surrounding intergenic sequences between the pro tRNA and 15 S rRNA genes. The deleted DNA has been sequenced and is found to be flanked by two 11 bp direct repeats. The deletion mutant displays a normal phenotype in non-fermentable media. This implies that the intergenic sequence is not required for expression of the respiratory phenotype. | |
Descriptors | DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC OXYGEN CONSUMPTION BASE SEQUENCE CHROMOSOME DELETION DNA RESTRICTION ENZYMES DNA, MITOCHONDRIAL MOLECULAR SEQUENCE DATA PHENOTYPE RNA, RIBOSOMAL RNA, TRANSFER SACCHAROMYCES CEREVISIAE |