Author/Editor     Zorman-Rojs, O; Čajavec, S; Ergotić, N; Josipović, D; Sladić, D; Mrzel, I; Lukežić, I
Title     Testing of two inactivated polyvalent vaccines gumpeskal+IB and nobi vac IB+G+ND in broiler breeder flocks
Type     članek
Source     Zb Vet Fak Univ Ljublj
Vol. and No.     Letnik 28, št. 2
Publication year     1991
Volume     str. 167-75
Language     eng
Abstract     The inactivated vaccine GumpeskalR + IB contains vaccinal strains of the Newcastle disease (NCD) virus, the infectious bursal disease (IBD) virus and of the infectious bronchitis (IB) virus. The strain of the NCD and IB viruses are inactivated with formalin, while the IBD virus is inactivated with beta - propionlakton and suspended in oil adjuvant. The harmlessness and immunogenicity of the vaccine were tested on three groups of light bred pullets at an age of 15 weeks, which were previously vaccinated with live vaccines against NCD, IBD and IB. One group of 20 animals was inoculated with 0.5 ml of the tested vaccine, the second group of 5 animals was inoculated with 1 ml of tested vaccine and another group of 10 animals served as control group. In a large field trial a 0.5 ml dose of the vaccine GumpeskalR + IB was applied to a group of 5500 broiler parents, at an age of 18 weeks. These animals were previously vaccinated with live vaccines according to the standard immunoprophylactic programme being used at the production farms. The polyvalent vaccine NOBIVAC IB + G + ND was applied to the same number of animals being bred in a neighbouring facility of the same farm. A quantitative immunodiffusion test (ID) with the IBD virus showed a significant increase of the titer of specific antibodies in the sera of pullets 14 days after vaccination with inactivated vaccine GumpeskalR + IB (for a factor of 2.1). The results of a haemmagglutination inhibition test performed 14 days after vaccinabeen vaccinated with inactivated vaccines, was tested using an ID test for the tion showed the increase of antibody for NCD virus by a factor of 3.1. The immune response in the sera of both groups of broiler parents, which had IBD and IB virus, and an HI test for the NCD virus, The ID test showed high percentages of positive reactors to the IBD and IB virus during the entire testing period.(trunc.)
Descriptors     VIRAL VACCINES
IMMUNITY
POULTRY
NEWCASTLE DISEASE VIRUS
INFECTIOUS BRONCHITIS VIRUS, AVIAN
VIRUS DISEASES