Author/Editor		Kenda, R
Title		Vezikoureteralni reflux in ledvične brazgotine pri asimptomatskih sorojencih otrok z vezikoureteralnim refluksom
Translated title		Vesicoureteral reflux and renal scars in asymptomatic siblings of children with reflux
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1992
Volume		str. 41
Language		slo
Abstract		The purpose of the study was to determine the incidence of vesicoureteral reflux (VUR), renal scars and hypertension in asymptomatic siblings of children with VUR.105 siblings of patients with VUR were studied. Their age ranged from 4 months to 6 years and 4 months. All had a direct radionuclide voiding cystography (DRVC) performed. VUR was detected in 47/105 (45 per cent ). Most high grade VUR were seen within the first year of age, their incidence being 50 per cent compared with a 9 per cent incidence in siblings older than 2 years. Only 1 of the 27 siblings with VUR grade 1 was younger than 1 year. In 43 of 47 siblings with VUR, 99mTc-DMSA was performed and renal scars were found in 10, which presents 23 per cent of siblings with VLTR and 10 per cent of all siblings studied. One child had hypertension. Identifying VUR among asymptomatic siblings could possibly prevent renal damage and its consequences. The predictive value of positive family history alone in identifying VUR was 45 per cent and 23 per cent of siblings with VUR were found to have renal scars. This appears high enough to justify the routine investigation of asymptomatic siblings, by using DRVC at an early age.
Descriptors		VESICO-URETERAL REFLUX CICATRIX KIDNEY DISEASES FAMILY HEALTH PREDICTIVE VALUE OF TESTS CHILD CHILD, PRESCHOOL INFANT PATENTS URINE SPECIMEN HANDLING KIDNEY BLADDER