| Author/Editor | Flynn, Daniel Christopher; Darwin-Nulton, James; Salamon, Peter; Frey, Terrence Gene; Rabinovitch, Avinoam; Sun, Mei Guo; Baljon, Arlette Rose Cornelia | |
| Title | A sterological unfolding method for the study of the mitochondrial network | |
| Type | članek | |
| Source | Image Anal Stereol | |
| Vol. and No. | Letnik 28, št. 1 | |
| Publication year | 2009 | |
| Volume | str. 11-22 | |
| Language | eng | |
| Abstract | When the mitochondrial network within the cell is in a fragmented state, it resembles a spatial distribution of prolate spheroids of various shapes, sizes and orientations. This paper presents a maximum-likelihood scheme for inferring the distribution of spheroidal shapes, sizes and orientations from the observed distribution of elliptical sections. We also present a parametric bootstrap suitable for inferring confidence intervals for the parameters describing the shape and size distribution of the spheroids. | |
| Descriptors | PARTICLE SIZE MITOCHONDRIA IMAGE PROCESSING, COMPUTER-ASSISTED MICROSCOPY, ELECTRON APOPTOSIS HELA CELLS |