| Author/Editor | Gabrijelčič, T | |
| Title | Pomen encimov za diagnozo perioperativnega miokardnega infarkta pri premostitvenih posegih na venčnih arterijah | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Medicinska fakulteta | |
| Publication year | 1993 | |
| Volume | str. 74 | |
| Language | slo | |
| Abstract | A hypothesis of peak of serum activity of isoenzyme CK-MB occuring 18-21 hours after the operation in patients, suffering from perioperative myocardial infarction (PMI) in contrast to expected earlier peak (3-8 hours after surgery) in patients without this complication was tested. Twenty-seven patients undergoing coronary artery bypass procedure exclusively were included. Mean age was quite low (56,8 years, range 41 to 75 years), but most of patients were very symptomatic (functional class III of angina in 41 per cent , class IV in 44 per cent and unstable angina in 18 per cent of cases) and had very advanced coronary disease (double vessel in 22 per cent , triple vessel in 70 per cent and left main disease in 11 per cent of cases). The mean number of distal anastomoses per patient was 4,52 and in 85 per cent of cases a combination of saphenous vein and internal mammary artery bypasses were performed. Patients were divided in two groups (group l: without -13 patients and group 2: with PMI -14 patients) on a basis of scintigraphy with antimyosin antibodies. Scintigraphy was performed 48 and 72 hours after application of radiopharmaceutical (Myoscint, 74 MBq 111In) on 6th day after operation. Planar images were obtained in three projections ( left anterior oblique, anterior and left lateral) and myocardial uptake was estimated using semiquantitative gradation (0-3). Grades 0 and 1 were considered negative and grades 1 and 2 positive regarding PMI. Myocardial perfusion scintigraphy (2olTl, 67-74 MBq) after pharmacodynamical 16), with wounds closed and partialy rehabilitated. stress (dipyridamole 0.5 mg/kg body weight) before operation and l2th day after the procedure was used to assess myocardial hypoperfusion in the sarne projections in planar technique.(trunc.) | |
| Descriptors | CORONARY ARTERY BYPASS MYOCARDIAL INFARCTION CREATINE KINASE CREATINE KINASE ISOENZYMES LACTATE DEHYDROGENASE CORONARY DISEASE ELECTROMYOGRAPHY HEART LACTATE DEHYDROGENASE ISOENZYMES |