Author/Editor		Neubauer, D; Osredkar, D; Paro-Panjan, D; Derganc, M
Title		Neurophysiological studies during early life
Type		članek
Source		Paediatriki
Vol. and No.		Letnik 72
Publication year		2009
Volume		str. 259-70
Language		eng
Abstract		The main aims in managing sick newborn infants are to prevent or at least minimize brain injury and to establish optimal neuro-developmental outcome. Electroencephalography (EEG), which reflects brain electrical activity, is regarded as the most reliable tool for the recognition of possible central nervous system (CNS) dysfunction (e.g. seizures) and for predicting outcome. The best surveillance of the neonate and young infant can be achieved by continuous functional monitoring, but long term EEG is of limited availability in many centres and requires interpretation bya skilled paediatric electroencephalographer.Amplitude-integrated EEG (aEEG) is a technique for simplified EEG monitoring that has clinical potential in neonatal intensive care (IC), and which has recently been reintroduced in IC settings as a valuable and reliable tool for the continuous monitoring of brain acrivity. Cardiorespiratory function is usually continuously monitored in IC units (ICUs), neonatal, paediatric and adult. The technique of continuous monitoring ofcardiorespiratory function (CMCRF) comprises 24-hour detection ofvarious cardiorespiratory functions, including bi-level respiration (nasai and thoraco-abdominal), heart rate, electrocardiograph (ECG), oxygen saturation, actimetry and snoring. This technique is often called simplified polysomnography (PSG) and is easily applied in neonates and infants. This article is composed of two parts, the first of which discusses data from recent literature and presents the experience of the authors with the diagnostic possibilities of both standard (digitalized and video-assisted) EEG and aEEG, stressing the importance of using new generation machines that incorporate a display of the raw EEG, along with the aEEG signal, for better seizure detection. The second part deals with the problem of sleep disordered breathing (SOB) during early life. (Abstract truncated at 2000 characters)
Descriptors		ELECTROENCEPHALOGRAPHY SEIZURES SLEEP APNEA SYNDROMES HYPOVENTILATION SNORING INFANT, NEWBORN INFANT HEART RATE POLYSOMNOGRAPHY ELECTROCARDIOGRAPHY