Author/Editor     Denišlič, M; Pirtošek, Z; Vodušek, DB; Zidar, J; Meh, D
Title     Botulinum toxin in the treatment of neurological disorders
Type     članek
Source     Ann N Y Acad Sci
Vol. and No.     Letnik 710
Publication year     1994
Volume     str. 76-87
Language     eng
Abstract     Botulinum toxin therapy is safe and effective in the treatment of different movement disorders, especially focal dystonias. We reviewed botulinum toxin treatment of 97 patients: 36 had blepharospasm, 41 had torticollis, and 20 had diverse movement disorders. Patients with blepharospasm and torticollis improved markedly after botulinum toxin injections. The most common side effect in BS patients was ptosis (44.4 percent); in TC patients, it was dysphagia (29.3 percent). The mean duration of the improvement in both groups was 3.4 months. Very promising results were obtained also in the heterogeneous group including patients with other focal dystonias and cerebral palsy. On the basis of these results, we concluded that BTA injections must now be considered the mainstay of therapy for focal dystonias and other involuntary movement disorders.
Descriptors     BLEPHAROSPASM
BOTULINUM TOXINS
MOVEMENT DISORDERS
TORTICOLLIS
ADOLESCENCE
ADULT
AGED
AGED, 80 AND OVER
BLEPHAROSPASM
BOTULINUM TOXINS
CHILD
MIDDLE AGE
MOVEMENT DISORDERS
TORTICOLLIS