Author/Editor | Vlaisavljević, Veljko; Kovač, Vilma; Čižek-Sajko, Mojca | |
Title | Impact of insulin resistance on the developmental potential of immature oocytes retrieved from human chorionic gonadotropin-primed women with polycystic ovary syndrome undergoing in vitro maturation | |
Type | članek | |
Source | Fertil Steril | |
Vol. and No. | Letnik 91, št. 3 | |
Publication year | 2009 | |
Volume | str. 957-9 | |
Language | eng | |
Abstract | In a homeostasis model assessment-insulin resistance (HOMA-IR)-positive group of women with polycystic ovary syndrome undergoing in vitro maturation (IVM), the maturation rate of immature oocytes was significantly lower compared with a HOMA-IR negative group of women (47% vs. 59%). The results of our study showed that IR and hyperinsulinemia have an adverse effect on the developmental potential of immature oocytes retrieved in the IVM procedure. | |
Descriptors | FERTILIZATION IN VITRO POLYCYSTIC OVARY SYNDROME INSULIN RESISTANCE OOCYTES |