Author/Editor     Vlaisavljević, Veljko; Kovač, Vilma; Čižek-Sajko, Mojca
Title     Impact of insulin resistance on the developmental potential of immature oocytes retrieved from human chorionic gonadotropin-primed women with polycystic ovary syndrome undergoing in vitro maturation
Type     članek
Source     Fertil Steril
Vol. and No.     Letnik 91, št. 3
Publication year     2009
Volume     str. 957-9
Language     eng
Abstract     In a homeostasis model assessment-insulin resistance (HOMA-IR)-positive group of women with polycystic ovary syndrome undergoing in vitro maturation (IVM), the maturation rate of immature oocytes was significantly lower compared with a HOMA-IR negative group of women (47% vs. 59%). The results of our study showed that IR and hyperinsulinemia have an adverse effect on the developmental potential of immature oocytes retrieved in the IVM procedure.
Descriptors     FERTILIZATION IN VITRO
POLYCYSTIC OVARY SYNDROME
INSULIN RESISTANCE
OOCYTES