| Author/Editor | Skok, Pavel; Ocepek, Andreja; Genslitskaya, Ekaterina; Kavalar, Rajko | |
| Title | Peutz-Jegherjev sindrom: predstavitev bolnika in pregled literature | |
| Translated title | Peutz-Jeghers syndrome: presentation of a patient and literature review | |
| Type | članek | |
| Source | Zdrav Vestn | |
| Vol. and No. | Letnik 78, št. 10 | |
| Publication year | 2009 | |
| Volume | str. 570-5 | |
| Language | slo | |
| Abstract | Introduction: Colorectal cancer carcinogenesis is a complex, long-lasting multistep process. Patients with dif erent polyposis syndromes, including Peutz-Jeghers, have signii cantly increased risk for dif erent types of cancer. Patients and methods: In this paper the authors are presenting a patient with Peutz-Jeghers syndrome, the clinical characteristics of this disease, molecular and genetic features, associations with carcinogenesis and screening possibilities. h is syndrome, characterized by the development of hamartomatous polyps in the gastrointestinal tract and mucocutaneus hiperpigmentations, was first described in a Dutch family in 1921 and is associated with increased risk of malignancy for the patient and his relatives.Conclusions: Early diagnosis of Peutz-Jeghers syndrome is important for the prevention and/or early detection of cancer. | |
| Descriptors | PEUTZ-JEGHERS SYNDROME COLONOSCOPY AGED |