Author/Editor		Pečovnik-Balon, Breda; Krajnc, Mitja
Title		Kostne spremembe in koronarne kalcifikacije pri bolnikih s sladkorno boleznijo in pri bolnikih, zdravljenih s hemodializo
Translated title		Bones disease and coronary calcifications in diabetic patients and in patients, treated with haemodialysis
Type		članek
Source		In: Čokolič M, editor. Novosti v osteologiji: monografija vabljenih predavanj II. osteoloških dnevov; 2009 okt 9-10; Maribor. Maribor: Univerzitetni klinični center,
Publication year		2009
Volume		str. 124-32
Language		slo
Abstract		In the article, we discuss the bone disease in patients with diabetes mellitus and patients, treated with haemodialysis. Risk of fracture is increased in diabetics, mineral bone density is lowered in type 1 diabetics and normal or increased in type 2 diabetics. Patients with chronic kidney disease can develop renal osteodystrophy (chronic kidney disease-mineral and bone disorder), which is associated with greater risk of fracture. In both groups of patients, there are some dilemmas about the diagnostics and treatment of bone disease. We mention the probable connection between arterial calcifications (that develop actively and in regulated manner) and bone disease.
Summary		V prispevku obravnavamo kostne spremembe pri bolnikih s sladkorno boleznijo in bolnikih, zdravljenih s hemodializo. Pri bolnikih s sladkorno boleznijo je tveganje za zlom večje, mineralna kostna gostota je znižana pri bolnikih s sladkorno boleznijo tipa 1 in normalna ali povišana pri bolnikih s sladkorno boleznijo tipa 2. Pri bolnikih s kronično ledvično boleznijo se pojavlja renalna osteodistrofija (oz. mineralne in kostne motnje pri kronični ledvični bolezni, CKD-MBD), ki je povezana s povečanim tveganjem za zlom. Pri obeh skupinah bolnikov se pojavljajo nekatere dileme glede diagnostike in zdravljenja kostne bolezni. Omenjamo verjetno povezavo med arterijskimi kalcifikacijami, katerih nastanek je aktiven in reguliran proces, in kostno prizadetostjo.
Descriptors		DIABETES MELLITUS BONE DISEASES