Author/Editor		Meglič, A; Meglič, L
Title		Sproščanje tkivnega aktivatorja plazminogena med porodom in po njem
Translated title		Release of tissue plasminogen activator during and after delivery
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 32, št. 2
Publication year		1993
Volume		str. 207-26
Language		slo
Abstract		In late pregnancy and dunng aeiivery, blood tibrinolytic activity significantly changes. Those changes may be caused by chariged levels of oxytocin and prolactin during and after delivery. Changes in oxytocin and prolactin levels and in individual components of fibrinolytic system were determined in blood of fiffeen women, who had vaginal delivery (group V) and in fiffeen women who delivered by caesarean section (group C). Fibrinolytic parameters (unspecific fibrinolytic activity, activity and antigen of tissue plasminogen activator, activity of inhibitor of plasminogen activator and antigen of endothelial inhibitor of plasminogen activator) and hormones were determined before delivery, during the first stage of delivery, one hour affer delivery of placenta, and three and ten days affer delivery. Prior to and three and ten days affer delivery, fibrinolytic parameters were determined also affer stimulation by venous occlusion. No significant differences between the two groups were found. Correlations between fibrinolytic parameters and hormones were not significant either. Response to venous occlusion measured by some fibrinolytic parameters changed significantly affer delivery, though, the differences between groups were not significant. It was concluded that stress due to vaginal delivery was similar to stress affer caesarean section concerning most tibrinolytic parameters. The two hormones measured, probably have no affect on fibrinolysis during and affer delivery.
Descriptors		FIBRINOLYSIS FIBRINOLYTIC AGENTS ALTEPLASE LABOR CESAREAN SECTION PREGNANCY PLASMINOGEN INACTIVATORS