Author/Editor     Tršinar, Bojan; Kmetec, Andrej; Oblak, Ciril; Žumer-Pregelj, Mirjana; Tepeš, Bojan
Title     Efficasy of a citrate-enriched mineral beverage in the prevention of calcium urolithiasis
Translated title     Učinkovitost s citrati obogatenega mineralnega napitka pri preprečevanju nastanka kalcijevih kamnov v sečilih
Type     članek
Source     Zdrav Vestn
Vol. and No.     Letnik 79, št. 1
Publication year     2010
Volume     str. 7-18
Language     eng
Abstract     Background: The aim of our study was toevaluate the effi cacy of a new citrate-enriched natural mineral beverage in the prevention of calcium stone formation in the urinary tract. Methods: Thirty-four patients, 16 male and 18 female, between 23 and 71 years of age (average 50.9 years), participated in a prospective, randomized, single-blind study that lasted two years. The patients were randomly divided into a study group (16 patients) and a control group (18 patients). All patients suff ered from recurrent urinary calcium stone disease, with at least one recurrence experienced within the previous two years. Before the start of the study, we evaluated the patients' dietary habits and fluid intake recorded the demographic and vital data, performed a blood count, biochemical analysis of blood and analysis of a 24-hour urine specimen, and obtained a plain x-ray film and/or ultrasound scan of the urinary tract to establish the presence of any urinary stones. Over the following two years, the patients of the study group drank 500 ml of the citrate-enriched mineral beverage daily, while the patients of the control group drank the same quantity of plain water. At the end of this treatment, each patient's health status was assessed and the initial laboratory investigations were repeated. Statistical analysis of the results was performed with the use of the chi-square test, Fischer's test and the Cochram-Mante-Haenszel test for qualitative variables; the two-tailed t test (comparison between groups) and the paired t test (comparisons within individual group) were used for quantitative variables. (Abstract truncated at 2000 characters)
Descriptors     URINARY CALCULI
CALCIUM
MINERAL WATERS
CITRATES
URINALYSIS
RANDOMIZED CONTROLLED TRIALS