Author/Editor		Skačej, Helena; Gračner, Tomaž; Pahor, Dušica
Title		Epidemiologija, klinične značilnosti, diagnostika in zdravljenje bolnikov s skleritisom v zadnjih 10 letih
Translated title		Epidemiology, clinical features, diagnostic procedures, and treatment of scleritis patients in the past 10 years
Type		članek
Source		In: Pahor D, Čizmarevič B, editors. Zbornik predavanj in praktikum Strokovni simpozij ob 90. obletnici ustanovitve Oddelka za očesne, ušesne, nosne in vratne bolezni UKC Maribor; 2009 nov 12; Maribor. Maribor: Univerzitetni klinični center,
Publication year		2009
Volume		str. 173-82
Language		slo
Abstract		Background. Scleritis is a rare and serious ocular disease, which is sometimes not easy to recognise. Further, an associated systemic illness may coexist. The article shows clinical characteristics of scleritis patients treated at our department in the past 10 years. Methods. A retrospective study was performed comprising medical records of all scleritis patients who were hospitalised at the Department of Ophthalmology, University Clinical Centre Maribor, from April 1, 1999 to April 1, 2009. Patient gender, age, type of scleritis, clinical features, involvement of one or two eyes, visual acuity at admission and discharge, diagnostic procedures, associated systemic diseases, treatment, complications, relapses of scleritis, and the working diagnosis set by general ophthalmologists were analysed. Results. 20 patients (25 eyes) were identified with the diagnosis of scleritis. The mean patient age was 58,0 +/- 16,2 years. There was a female predominance (60 %). Anterior scleritis was observed in 9 out of 25 eyes (36%), while signs of posterior scleritis were found in 16 out of 25 eyes (64 %). All participants experienced ocular pain. Eye redness and fundus changes were detected in 92 % and 24 % of examined eyes, respectively. Simultaneous bilateral involvement occured in two patients (10 %). The average best corrected visual acuity was 0, 7 +/- 0,3 at admission and 0,8 +/- 0,3 at discharge. Moreover, ocular ultrasound examination and diagnostic procedures for systemic diseases were performed. The latter included: basic laboratory, rheumatological, serological, and tuberculin tests, as well as imaging and consultations with other specialists. Two patients suffered from Wegener's granulomatosis, one from rheumatoid arthritis and one from a Toxocara canis infection. The principal treatment mode was the use of systemic corticosteroids. In 20 % of eyes scleritis - induced scleral thinning was observed. (Abs. trunc. at 2000 ch.)
Summary		Izhodišča. Skleritis je redko, resno in včasih težje prepoznavno obolenje. Lahko mu je pridružena življenjsko ogrožujoča sistemska bolezen. Namen je prikazati klinične značilnosti bolnikov s skleritisom, ki so bili zdravljeni na našem oddelku v zadnjih 10 letih. Metode. Opravljena je bila retrospektivna raziskava medicinske dokumentacije vseh bolnikov s skleritisom, ki so bili hospitalizirani na Oddelku za očesne bolezni Univerzitetnega kliničnega centra Maribor v obdobju od 1. 4. 1999 do 1. 4. 2009. Analiza je zajela spol, starost bolnikov, vrsto skleritisa, simptome in znake, prizadetost enega ali obeh oči, vidno ostrino ob sprejemu in odpustu, diagnostične postopke, morebitne pridružene sistemske bolezni, zdravljenje, zaplete, ponovitve bolezni ter delovne diagnoze napotnih oftalmologov. Rezultati. V opazovanem obdobju je bilo obravnavanih 20 bolnikov (25 oči) s skleritisom. Povprečna starost preiskovancev je bila 58,0 +/- 16,2 let. Prevladovale so ženske (60 %). Pri 9 izmed 25 oči (36 %) je bil prisoten anteriorni skleritis, pri 16 od 25 oči (64 %) pa tudi znaki posteriornega skleritisa. Vsi bolniki so tožili zaradi bolečine v področju obolelega očesa. Pri 92 % oči je bila vidna draženost zrkla, pri 24 % pa tudi spremembe na očesnem ozadju. Pri dveh bolnikih (10 %) se je skleritis pojavil obojestransko. Povprečna korirgirana vidna ostrina je bila na prizadetem očesuob sprejemu 0,7 +/- 0,3, ob odpustu pa 0,8 +/- 0,3. Opravljeni so bili ultrazvok zrkel in orbit ter preiskave v smislu iskanja sistemskih obolenj, kot so: osnovne laboratorijske, revmatološke in serološke preiskave, antituberkulinski test, slikovna diagnostika ter posveti z drugimi specialisti. Ena preiskovanka je imela revmatoidni artritis, dva preiskovanca Wegenerjevo granulomatozo, eden okužbo s Toxocaro canis. Vsi bolniki so prejeli sistemsko kortikosteroidno zdravljenje. Pri petini oči se je kot posledica skleritisa pojavila stanjšanost beločnice. (Izvl. skrajšan na 2000 zn.)
Descriptors		SCLERITIS