Author/Editor		Humolli, Isme; Dedushaj, Isuf; Avšič-Županc, Tathana; Mucaj, Sefedin
Title		Epidemiological, serological and herd immunity of Crimean-Congo Haemorrhagic Fever in Kosovo
Type		članek
Source		Med Arh
Vol. and No.		Letnik 64, št. 2
Publication year		2010
Volume		str. 91-3
Language		eng
Abstract		Crimean-Congo Haemorrhagic Fever (CCHF) is primarily a zoonotic disease, mostly present as sporadie cases, but outbreaks also oceur, especially in the family. Disease as endemic form is presents in some countries of Africa, Europe and Asia. In 2001, outbreakofCCHFwas registered in Kosova, Albania, Pakistan,lran, and South Africa. Goal of the research was to establish a pattern of the disease, its natural flow and herd immunity. Forthis purpose we used epidemiological methods, laboratory confirmation (ELlSA, PCR) and t-test and X2-test for results significance verification. Morbidity rate of the disease forthe period offifteen years (19952009) is 0-49 in 100 000 inhabitants, and lethality rate is 26.76 deaths on 100 lab confirmed cases. CCHF in Kosovo is present in 50% of the territory with common characteristics: altitude, hot c1imate, low bush and farming. Hyper endemic zones are in Central and South West of Kosovo. Seroprevalence in entire healthy population is found to be 24.3%. Presence of the CCHF antibodies was found in 14% oflivestock, and in 32.6% ofsheep. A phylogenetic aspect of the CCHF virus isolated in Kosovo is the same as of the virus isolated in Drosdov (Russia).
Descriptors		HEMORRHAGIC FEVER, CRIMEAN HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO ENZYME-LINKED IMMUNOSORBENT ASSAY POLYMERASE CHAIN REACTION PHYLOGENY ANIMALS, DOMESTIC SHEEP IGM IGG