| Author/Editor | Mišič-Majerus, Lilijana; Ðaković-Rode, Oktavija; Ružić-Sabljić, Eva; Bujić, Nevenka; Mađarić, Vesna; Kolarić, Gordana | |
| Title | Predviđanje težine krpeljnog meningoencefalitisa na temelju izabranih pokazatelja | |
| Translated title | Prognosis of severity of tick-borne encephalitis based on selected parameters | |
| Type | članek | |
| Source | Infektol Glas | |
| Vol. and No. | Letnik 30, št. 1 | |
| Publication year | 2010 | |
| Volume | str. 11-20 | |
| Language | cro | |
| Abstract | The main purpose of our study was to investigate whether the severity and course of acute il1ness in patients with tick-bome encephalitis can be predicted based on selected parameters determined on admission to ho spi tal. This retrospective study included adult patients with TBE, who were treated at the Department ofInfectious Diseases, General Hospital, Koprivnica, Croatia, between 1995 and 2005. Case records of all patients were reviewed. On admission to hospital the acute meningoencephalitic (ME) stage was classified as mild or severe, depending on the presence of meningeal symptoms, the severity of clinic al signs of encephalitis and presence of focal central nerves systems (CNS) signs. The patients were generally examined and categorized by the same physician. We analyzed and compared selected parameters determined on admission to hospital including: sex and age, multiple tick bite, seasonal distribution, period oftime (days) between the onsetoffirst symptoms of disease and the first examination, duration of asymptomatic interval ( days), state of mind, course of illness (biphasic, monophasic), cerebrospinal fluid and peripheral blood findings, concomitant infection with Borrelia burgdorferi sensu lato (BBSL). All data collected from patients were entered into specially prepared questionnaire. Recent infection with TBE was confirmed in 133 patients, 83 (62,4 %) male s and 50 (37,6 %) females, aged 16 to 76. Ahistory oftick-bite was noted in 86 (64,6%) ofwhom multiple in 33 (38,3 %) patients. TBE presented as isolated meningitis in 50 (37,6 %), as ME in 66 (49,6 %) and as meningoencephalomyelitis (MEM) in 17 (12,8 %) patients. A biphasic course of disease occurred in 94 (70,7 %) patients. Mild ME stage was noticed in 77 (57,8 %) and severe in 56 (42,1%) patients. (Abstract truncated at 2000 characters) | |
| Descriptors | ENCEPHALITIS, TICK-BORNE SEVERITY OF ILLNESS INDEX |