Author/Editor     Grgič-Vitek, Marta; Avšič-Županc, Tatjana; Klavs, Irena
Title     Tick-borne encephalitis after vaccination: vaccine failure or misdiagnosis
Type     članek
Source     Vaccine
Vol. and No.     Letnik 28, št. 46
Publication year     2010
Volume     str. 7396-400
Language     eng
Abstract     The aim of the paper is to present the results of the investigation of a series of four cases of tick-borne encephalitis (TBE) reported from Gorenjska region in Slovenia in 2008 despite vaccination against TBE, propose surveillance case definition for TBE and classification criteria for TBE vaccine failure cases, to discuss challenges in the interpretation of TBE serology results in previously vaccinated patients and propose ascertainment procedures for vaccine failure cases. Establishing surveillance of vaccine failure cases on national and European level is essential for monitoring and evaluating the impact of immunization, evaluation of vaccine effectiveness and early warning for the need to change the vaccination schedule recommendations.
Descriptors     ENCEPHALITIS, TICK-BORNE
VIRAL VACCINES
ENCEPHALITIS VIRUSES, TICK-BORNE
ANTIBODIES, VIRAL
IGG
IGM
DIAGNOSTIC ERRORS